An ion channel is a pore-forming protein that helps to establish and control the small voltage gradient across the plasma membrane of all living cells (see resting potential) by allowing the flow of ions down their electrochemical gradient. They are present in the membranes that surround all biological cells.
An ion channel is an integral membrane protein or more typically an assembly of several proteins.
- "Press Release: Nobel Prize in Chemistry 2003". Nobel Media AB. Retrieved 2011-10-02.
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- An Interview with Roderick MacKinnon Freeview video by the Vega Science Trust.
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- X-ray crystal structure of a potassium channel Archived 2009-09-26 at the Wayback Machine
- Neuromuscular Disease Center at Washington University
- Nobel Prize Press Release
- International Union of Pharmacologists, Ion channel compendium Archived 2007-03-06 at the Wayback Machine