Protein biosynthesis

cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain

Protein biosynthesis (synthesis) is when cells build proteins. The term is sometimes used to refer only to protein translation but more often it refers to a multi-step process.

Amino acids are either synthesised or eaten in food. Then, after the transcription of polypeptide genes, the amino acids are put together. This is done by translation and RNA splicing which produces messenger RNAs. The splicing process produces the final proteins, which then fold up into their protein structure. Then they can function. The plural is used here because, with most genes, the splicing process produces more than one final working protein. One particular Drosophila gene (DSCAM) can be alternatively spliced into 38,000 different mRNA.[1]

Protein biosynthesis differs between prokaryotes and eukaryotes, though parts of the process are the same in both.

References change

  1. Schmucker D.; et al. (2000). "Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity". Cell. 101 (6): 671–684. doi:10.1016/S0092-8674(00)80878-8. PMID 10892653. S2CID 13829976.

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