chemical compound

Pyrimidines include three of the bases in DNA and RNA.

Pyrimidine 2D aromatic full.svg
Pyrimidine 2D numbers.svg
Pyrimidine molecule
Pyrimidine molecule
IUPAC name
Other names
1,3-Diazine, m-Diazine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

A pyrimidine is an aromatic heterocyclic organic compound, similar to purine.[1] It has nitrogens at positions 1 and 3 in the ring.[2][3]


The pyrimidine ring system occurs widely in nature.[4]

It is also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Uric acid is a pyrimidine derivative.


  1. Gilchrist T.L. (1997). Heterocyclic chemistry. New York: Longman. ISBN 0-582-27843-0.
  2. Joule, John A.; Mills, Keith, eds. (2010). Heterocyclic chemistry (5th ed.). Oxford: Wiley. p. 250. ISBN 978-1-405-13300-5.
  3. Brown H.C. et al 1955. In Baude, E.A. and Nachod, F.C., Determination of organic structures by physical methods. Academic Press, New York.
  4. Lagoja, Irene M. (2007). "Pyrimidine as constituent of natural biologically active compounds" (PDF). Chemistry and Biodiversity. 2 (1): 1–50. doi:10.1002/cbdv.200490173. PMID 17191918.