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Antisuppressor is a mutation with the response against suppression effects of nonsense suppression or suppression chemicals.[1][2][3][2]

In 1976, Rieger, Michaelis, and Green have been stated:

"antisuppressor – a mutation which countreacts suppressor effects (→ nonsense suppression). Antisuppressor mutations can occur in any of the folowing components affecting the → genetic translation system (Cox 1973):

  1. A ribosomal component affecting codon-anticodon recognition or tRNA binding.
  2. A termination factor altered in such a way that synthesis polypeptide release from the ribosome is enhanced thus decreasing the efficiency of suppression.
  3. An enzyme affecting → suppressor tRNA (either an → aminoacyl-tRNA synthetase, a base modifying enzyme affecting the anticodon, an enzyme modifaying a base or bases involved in ribosome binding, an enzyme affecting tRNA maturation, or a factor controling total tRNA)."[4]

See alsoEdit


  1. Rmolecular. Heidelberg - New York: Springer-Verlag. ISBN 3-540-07668-9. Missing or empty |title= (help)CS1 maint: uses authors parameter (link)
  2. 2.0 2.1 King R. C., Stransfield W. D. (1998). Dictionary of genetics. New York, Oxford: Oxford niversity Press. ISBN 0-19-50944-1-7.CS1 maint: uses authors parameter (link)
  3. Hadžiselimović R., Pojskić N. (2005). Uvod u humanu imunogenetiku. Institut za genetičko inženjerstvo i biotehnologiju (INGEB), Sarajevo. ISBN 9958-9344-3-4.
  4. Rieger R. Michaelis A., Green M. M. (1976). Glossary of genetics and cytogenetics: Classical and molecular. Heidelberg - New York: Springer-Verlag. ISBN 3-540-07668-9.CS1 maint: uses authors parameter (link)