Biochemical cascade

series of chemical reactions which are initiated by a stimulus acting on a receptor that is transduced to the cell interior through second messengers and ultimately to effector molecules, resulting in a cell response to the initial stimulus

A biochemical cascade (or signalling pathway) is a series of chemical reactions. It is started by a stimulus (first messenger) acting on a receptor. The 'message' is passed on to the cell interior through other reactions. These later chemical reactions amplify (build up) the initial signal. Eventually there is a cell response to the initial stimulus.[1] The passing series of chemical changes is a cascade, and the whole process is called signal transduction.


  1. Gomperts B.D; Kramer I.M. & Tatham P.E.R. (2004). Signal transduction. Amsterdam: Elsevier Academic Press. ISBN 978-0122896323.{{cite book}}: CS1 maint: multiple names: authors list (link)