Cerebral amyloid angiopathy

amyloidosis where amyloid protein progressively deposits in cerebral blood vessel walls with subsequent degenerative vascular changes

Cerebral amyloid angiopathy (CAA), also known as congophilic angiopathy,[1] is a form of angiopathy in which amyloid comes out of the walls of the blood vessels of the central nervous system.[2]

The term congophilic is used because the amyloid appears red when looked under a microscope when Congo red dye is used. The amyloid material is only found in the brain and as such the disease is not related to other forms of amyloidosis.[3]

References

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  1. Exley C, Esiri MM (July 2006). "Severe cerebral congophilic angiopathy coincident with increased brain aluminium in a resident of Camelford, Cornwall, UK". J. Neurol. Neurosurg. Psychiatry. 77 (7): 877–9. doi:10.1136/jnnp.2005.086553. PMC 2117501. PMID 16627535.
  2. "Cerebral amyloid angiopathy: MedlinePlus Medical Encyclopedia". www.nlm.nih.gov. Retrieved 2015-05-27.
  3. Newfoundland, FRCP William Pryse-Phillips MD, FRCP(C) Faculty of Medicine Health Sciences Centre Memorial University of Newfoundland St John's (2009-05-06). Companion to Clinical Neurology. Oxford University Press, USA. ISBN 9780199710041.{{cite book}}: CS1 maint: multiple names: authors list (link)