Chronic traumatic encephalopathy

neurodegenerative disease caused by head injury

Chronic traumatic encephalopathy (CTE), formerly known as dementia pugilistica, is a neurodegenerative disease found in people who have had multiple head injuries.[1] These injuries can be from contact sports such as American football or boxing, as well as from military service, domestic violence and other causes.

Comparison between a normal brain (left) and a brain with advanced CTE (right)

Symptoms may include behavioral problems, mood problems, and problems with thinking. It can also cause problems with balance, moving and speaking. This typically does not begin until years after the injuries. It often gets worse over time and can result in dementia.[2] It is unclear if the risk of suicide is increased. Doctors can only tell for sure if somebody has CTE by looking at their brain after they die.

References

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  1. Asken, BM; Sullan, MJ; DeKosky, ST; Jaffee, MS; Bauer, RM (1 October 2017). "Research Gaps and Controversies in Chronic Traumatic Encephalopathy: A Review". JAMA Neurology. 74 (10): 1255–1262. doi:10.1001/jamaneurol.2017.2396. PMID 28975240. S2CID 24317634.
  2. Stein, TD; Alvarez, VE; McKee, AC (2014). "Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel". Alzheimer's Research & Therapy. 6 (1): 4. doi:10.1186/alzrt234. PMC 3979082. PMID 24423082.