The Cosmic Cube is a fictional object in the Marvel Comics universe that has immense reality-altering powers. Although the first version, introduced in Tales of Suspense #79 (July 1966) and created by Stan Lee and Jack Kirby, originated on Earth as a weapon built by Advanced Idea Mechanics, most are of alien origins. It can reshape reality and manipulate matter on a vast scale. It has been featured in various comic book storylines, often as a powerful and dangerous artifact sought after by villains and heroes alike.

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The Cube (renamed the Tesseract) plays a central role in several movies of the Marvel Cinematic Universe, in which it is ultimately depicted as containing the Space Stone, one of the six Infinity Stones.