Ketoacidosis

metabolic condition

Diabetic ketoacidosis (DKA) is caused by untreated high blood glucose (hyperglycemia). If does not get treated, it can develop into a life threatening sickness. In this state the body breaks down fat at a high rate.[1][2]

Total Ion Chromatogram of a urine sample in a patient with diabetic ketoacidosis. Urine organic acid analysis profile: The 3 prominent peaks on the left are from left to right: B-hydroxybutyrate, Acetoacetate (with TMS derivative 1), Acetoacetate 2nd peak (with TMS derivative 2). TMS = trimethylsilyl derivative reagent, PDA = pentadecanoic acid (internal standard).

Causes

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Diabetic ketoacidosis is caused by a lack of insulin and a high number of ketones, which causes blood to become acidic. This sickness is an emergency that can lead to coma or death.[2]

Symptoms of ketoacidosis include:[2]

Those with type 2 diabetes can also get sick with ketoacidosis. DKA can happen with high blood sugar, when medicine is stopped, because of a bad sickness or infection:[1]

References

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  1. 1.0 1.1 "Diabetic ketoacidosis: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2023-07-19.  This article incorporates text from this source, which is in the public domain.
  2. 2.0 2.1 2.2 2.3 "Diabetic ketoacidosis: Know the warning signs-Diabetic ketoacidosis - Symptoms & causes". Mayo Clinic. Retrieved 2023-07-19.
  3. "Hyperglycemia". Cleveland Clinic. Retrieved 2023-07-18.