Otto Loewi

Jewish-German pharmacologist

Otto Loewi (June 3, 1873 - December 25, 1961) was a German doctor.[1] He won the 1936 Nobel Prize in Physiology or Medicine, along with Henry Hallett Dale, for their discoveries about chemical transmission of nerve impulses [2]

Otto Loewi
BornJune 3, 1873
DiedDecember 25, 1961
NationalityGerman
CitizenshipAustrian (after 1905)
American (from 1946)
Alma materUniversity of Munich
University of Strassburg
AwardsNobel Prize in Physiology or Medicine (1936)
Scientific career
FieldsMedicine, Pharmacology
InstitutionsGraz University

In his most famous experiment, Loewi took fluid from a frog heart with a slowed beat and applied it to another. That slowed the second heart. This showed that synaptic signalling used chemical messengers.

It is now known that there are two different kinds of nerve synapses. One kind releases chemicals, and is a neurotransmitter synapse. The other is an electrical synapse which transmits voltage charges over gap junctions between nerve cells.

References

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  1. "Biography of Otto Loewi". The Nobel Foundation. Retrieved 2009-01-05.
  2. "The Nobel Prize in Physiology or Medicine 1936". The Nobel Foundation. Retrieved 2009-12-21.