Propranolol
beta blocker drug
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Propanolol (brand names Bedranol, Beta-prograne, Half Beta-prograne) belongs to a group of medicines called beta blockers. It is used to treat heart problems, help with some of the symptoms of anxiety and prevent migraines.[1]
For heart problems, propranolol can be taken to to:[1]
- treat high blood pressure
- treat conditions that cause an irregular heartbeat (arrhythmia), like atrial fibrillation
- help prevent future heart disease, heart attacks and stroke
- help prevent chest pain caused by angina
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| Clinical data | |
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| Pronunciation | /proʊˈprænəˌlɑːl/ |
| Trade names | Inderal, others |
| AHFS/Drugs.com | Monograph |
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| Routes of administration | Oral, rectal, intravenous |
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| Pharmacokinetic data | |
| Bioavailability | 26% |
| Protein binding | 90% |
| Metabolism | Liver (extensive) CYP1A2, CYP2D6; minor: CYP2C19, CYP3A4 |
| Metabolites | N-desisopropylpropranolol, 4'-hydroxypropanolol |
| Elimination half-life | 4–5 hours |
| Excretion | Kidney (<1%) |
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| ECHA InfoCard | 100.007.618 |
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| Chirality | Racemic mixture |
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References
change- ↑ 1.0 1.1 "Propranolol: medicine for heart problems, anxiety and migraine". nhs.uk. 2019-01-14. Retrieved 2024-06-04.