Crossing over

cellular process
(Redirected from Recombination)

Crossing over is a basic concept of genetics and cell biology, often called recombination. It occurs during meiosis.

Crossing over takes place between the chromatids of two homologous chromosomes. Maternal chromatids are red; paternal chromatids are blue. Lines point to the chiasmata (cross overs)

Crossing over is the exchange of chromosome segments between non-sister chromatids during the production of gametes. The effect is to assort (shuffle) the alleles on parental chromosomes, so that the gametes carry combinations of genes different from either parent. This has the overall effect of increasing the variety of phenotypes present in a population.

The process can be seen directly in stained cells, and indirectly if there are genetic markers or not on the chromosomes. The visible crossovers are called chiasma (plural: chiasmata), which is Greek for a cross. F. A. Janssens was the first to suggest what chiasmata meant.[1][2]

The large-scale effect of crossing over is to spread variation through a population. This is the main result of sexual reproduction compared to non-sexual modes of reproduction.

The main advantage to the parents is the greater variety in their offspring. This, it is thought, increases the chance that some of the offspring will survive and reproduce. This has been the subject of much investigation and discussion.[3]

References change

  1. Janssens F. A., 1909, La théorie de la chiasmatypie. La Cellule 25, 389–411.
  2. Sturtevant A. H., A history of genetics. Harper & Row, New York, pps. 77–79
  3. Thompdon J. N., 2013. Recombination and reproduction in Relentless evolution, pgs. 144–164. University of Chicago Press. ISBN 978-0-226-01875-1