Rudolf Anderson Jr. (September 15, 1927 – October 27, 1962), was a pilot and commissioned officer in the United States Air Force.
Rudolf Anderson Jr. was the only person killed by enemy fire during the Cuban Missile Crisis.
On October 27, Anderson took off in a U-2F (AF Serial Number 56-6676, former CIA Article 343) from a forward operating location at McCoy Air Force Base in Orlando, Florida. A few hours into his mission, he was shot down by a Soviet-supplied S-75 Dvina (NATO designation SA-2 Guideline) surface-to-air missile near Banes, Cuba. "The loss of the U-2 over Banes was probably caused by intercept by an SA-2 from the Banes site, or pilot hypoxia, with the former appearing more likely on the basis of present information," stated a CIA document dated 0200 hrs, October 28, 1962. Anderson was killed when shrapnel from the exploding proximity warhead punctured his pressure suit, causing it to decompress at high altitude.