Honeycutt played college basketball for the UCLA Bruins. Honeycutt was selected by the Sacramento Kings in the second round of the 2011 NBA draft. He played for the Kings for two seasons and in 2013 moved to Europe, where he played for EuroLeague clubs Khimki and Anadolu Efes.
On the night of July 6, 2018, Honeycutt's mother called the police and reported that Honeycutt had been acting violently. When police arrived they found that he had blocked the entrance to his Sherman Oaks home before shooting at them. He was later found dead, aged 27, inside the house after shooting himself.
- "Tyler Honeycutt dies following gunfire exchange with police". ESPN. July 7, 2018. Retrieved July 7, 2018.
- "Former UCLA star and NBA Player Tyler Honeycutt found dead following shootout with police". Yahoo! Sports. July 7, 2018. Retrieved July 7, 2018.