User:MdWikiBot/Autoimmune disease
Autoimmune disease | |
---|---|
Other names | Autoimmune condition |
Young woman with the typical "butterfly rash" found in systemic lupus erythematosus | |
Medical specialty | Rheumatology, immunology, gastroenterology, neurology, dermatology |
Symptoms | Depends on the condition. Commonly low grade fever, feeling tired[1] |
Usual onset | Adulthood[1] |
Types | List of autoimmune diseases (alopecia areata, celiac disease, diabetes mellitus type 1, Graves' disease, inflammatory bowel disease, multiple sclerosis, psoriasis, rheumatoid arthritis, systemic lupus erythematosus, others)[1] |
Medication | Nonsteroidal anti-inflammatory drugs, immunosuppressants, intravenous immunoglobulin[1][2] |
Frequency | 24 million / 7% (USA)[1][3] |
An autoimmune disease is a condition arising from an abnormal immune response to a functioning body part.[1] There are at least 80 types of autoimmune diseases.[1] Nearly any body part can be involved.[3] Common symptoms include low grade fever and feeling tired.[1] Often symptoms come and go.[1]
The cause is generally unknown.[3] Some autoimmune diseases such as lupus run in families, and certain cases may be triggered by infections or other environmental factors.[1] Some common diseases that are generally considered autoimmune include celiac disease, diabetes mellitus type 1, Graves' disease, inflammatory bowel disease, multiple sclerosis, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.[1][4] The diagnosis can be difficult to determine.[1]
Treatment depends on the type and severity of the condition.[1] Nonsteroidal anti-inflammatory drugs (NSAIDs) and immunosuppressants are often used.[1] Intravenous immunoglobulin may also occasionally be used.[2] While treatment usually improves symptoms, they do not typically cure the disease.[1]
About 24 million (7%) people in the United States are affected by an autoimmune disease.[1][3] Women are more commonly affected than men.[1] Often they start during adulthood.[1] The first autoimmune diseases were described in the early 1900s.[5]
References
change- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 "Autoimmune diseases fact sheet". Office on Women's Health. U.S. Department of Health and Human Services. 16 July 2012. Archived from the original on 5 October 2016. Retrieved 5 October 2016.
- ↑ 2.0 2.1 Katz U, Shoenfeld Y, Zandman-Goddard G (2011). "Update on intravenous immunoglobulins (IVIg) mechanisms of action and off- label use in autoimmune diseases". Current Pharmaceutical Design. 17 (29): 3166–75. doi:10.2174/138161211798157540. PMID 21864262.
- ↑ 3.0 3.1 3.2 3.3 Borgelt, Laura Marie (2010). Women's Health Across the Lifespan: A Pharmacotherapeutic Approach. ASHP. p. 579. ISBN 978-1-58528-194-7. Archived from the original on 2017-09-08.
- ↑ Hohlfeld R, Dornmair K, Meinl E, Wekerle H (February 2016). "The search for the target antigens of multiple sclerosis, part 1: autoreactive CD4+ T lymphocytes as pathogenic effectors and therapeutic targets". The Lancet. Neurology. 15 (2): 198–209. doi:10.1016/S1474-4422(15)00334-8. PMID 26724103. S2CID 20082472.
- ↑ Ananthanarayan R, Paniker CK (2005). Ananthanarayan and Paniker's Textbook of Microbiology. Orient Blackswan. p. 169. ISBN 9788125028086. Archived from the original on 2017-09-08.