VIPoma

rare endocrine tumor that overproduces vasoactive intestinal peptide

A VIPoma (Pronounced "V I P oma") (also called Verner Morrison syndrome after the doctors who first noticed it[1]), is a tumor that does not happen a lot (1 per 10,000,000 per year) in the pancreas.[2] VIPoma makes something called vasoactive intestinal peptide, or VIP. It can do bad things to the heart, brain, gut, gallbladder, and more.

Treatment

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Octreotide (a somatostatin analogue) can be used to help symptoms. Surgery is the only thing that will make it go away completely.

References

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  1. Verner JV, Morrison AB (Sep 1958). "Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia". Am J Med. 25 (3): 374–80. doi:10.1016/0002-9343(58)90075-5. PMID 13571250.
  2. Dorland's Medical Dictionary