Aspartic acid
chemical compound
Aspartic acid (symbol Asp or D;[4] is an α-amino acid that is used in the biosynthesis of proteins.[5] Like all other amino acids, it contains an amino group and a carboxylic acid. Aspartic acid has an acidic side chain (CH2COOH) which reacts with other amino acids, enzymes and proteins in the body.[5]
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IUPAC name
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3D model (JSmol)
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ChEBI |
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ECHA InfoCard | 100.000.265 | ||
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CompTox Dashboard (EPA)
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Properties | |||
C4H7NO4 | |||
Molar mass | 133.10 g·mol−1 | ||
Appearance | colourless crystals | ||
Density | 1.7 g/cm3 | ||
Melting point | 270 °C (518 °F; 543 K) | ||
Boiling point | 324 °C (615 °F; 597 K) (decomposes) | ||
4.5 g/L[2] | |||
Acidity (pKa) |
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Conjugate base | Aspartate | ||
-64.2·10−6 cm3/mol | |||
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |||
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It is a non-essential amino acid in humans, meaning the body can make it as needed. It is encoded by the codons GAU and GAC.
D-Aspartate is one of two D-amino acids commonly found in mammals.[3]
References
change- ↑ Budavari, Susan; Co, Merck (1989). "862. Aspartic acid". The Merck Index (11th ed.). p. 132. ISBN 978-0-911910-28-5.
- ↑ "ICSC 1439 - L-ASPARTIC ACID". inchem.org.
- ↑ Haynes, William M., ed. (2016). CRC Handbook of Chemistry and Physics (97th ed.). CRC Press. pp. 5–89. ISBN 978-1498754286.
- ↑ "Nomenclature and Symbolism for Amino Acids and Peptides". IUPAC-IUB Joint Commission on Biochemical Nomenclature. 1983. Archived from the original on 9 October 2008. Retrieved 5 March 2018.
- ↑ 5.0 5.1 G., Voet, Judith; W., Pratt, Charlotte (2016-02-29). Fundamentals of biochemistry : life at the molecular level. ISBN 9781118918401. OCLC 910538334.
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