|Classification and external resources|
Diagram of the lower gastrointestinal tract
|ICD-O:||M8140/3 (95% of cases)|
|eMedicine||med/413 med/1994 ped/3037|
Colorectal cancer, also known as colon cancer, rectal cancer, or bowel cancer, is a cancer in the colon or rectum (parts of the large intestine), or in the appendix. Genetic analysis shows that essentially colon and rectal tumours are genetically the same cancer. Symptoms of colorectal cancer typically include rectal bleeding and anemia which are sometimes associated with weight loss and changes in bowel habits.
It is estimated that worldwide, 1.23 million new cases of colorectal cancer are clinically diagnosed, and that it kills 608,000 people per year.
- Cancer Genome Atlas Network (19 July 2012). "Comprehensive molecular characterization of human colon and rectal cancer". Nature 487 (7407): 330–337. doi:10.1038/nature11252. PMC 3401966. PMID 22810696.
- Colorectal Cancer Incidence, Mortality and Prevalence Worldwide in 2008 — Summary. Available from: Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. (2010) GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet]. Lyon, France: International Agency for Research on Cancer. Accessed on 11 Oct 2012.