David Baltimore (born March 7, 1938 in New York City) is an American biologist. He won the Nobel Prize in Physiology or Medicine in 1975 for discovering reverse transcriptase. He shared the prize with Howard Temin and Renato Dulbecco.
The discovery of reverse transcriptase was made at the same time as Howard Temin. It overturned the central dogma of molecular biology because it showed that genetic information could traffic both ways between DNA and RNA. They published these findings in back-to-back papers in the journal, Nature.
- "David Baltimore - Autobiography". nobelprize.org. 2011 [last update]. Retrieved 27 February 2011. Check date values in:
- Baltimore, David (1970). "Viral RNA-dependent DNA polymerase: RNA-dependent DNA polymerasse in visions of RNA tumor viruses". Nature 226 (226): 1209–1211. doi:10.1038/2261209a0. PMID 4316300.
- Temin, Howard (1970). "Viral RNA-dependent DNA Polymerasse: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus". Nature 226 (226): 1211–1213. doi:10.1038/2261211a0. PMID 4316301.