Duke Charles Louis Frederick of Mecklenburg

German noble (1708-1752)

Charles Louis Frederick of Mecklenburg (23 February 1708 – 5 June 1752) was a prince in the House of Mecklenburg-Strelitz. He is also known as Prince of Mirow. He never reigned.

Two of his sons, Adolf Friedrich (IV) and Charles (II) became regents of Mecklenburg. His daughter, Sophie Charlotte became the queen of Great Britain, after marrying George III.