Joachim Frank

German-born American biophysicist and Nobel laureate

Joachim Frank (born September 12, 1940) is a German-born American biophysicist at Columbia University. He is thought to be as the founder of single-particle cryo-electron microscopy (cryo-EM). He shared the Nobel Prize in Chemistry in 2017 with Jacques Dubochet and Richard Henderson.[2] He also made major works to structure and function of the ribosome from bacteria and eukaryotes.

Joachim Frank
Joachim Frank.jpg
Joachim Frank under Nobel Prize press conference in Stockholm, December 2017
Born (1940-09-12) September 12, 1940 (age 82)
CitizenshipUnited States, Germany[1]
EducationUniversity of Freiburg (BS)
University of Munich (MS)
Max Planck Society
Technical University of Munich (PhD)
Known forSingle-particle cryo-electron microscopy
Ribosome structure and dynamics
Carol Saginaw (m. 1983)
ChildrenZe Frank & Mariel Frank
AwardsBenjamin Franklin Medal in Life Science (2014)
Wiley Prize in Biomedical Sciences (2017)
Nobel Prize in Chemistry (2017)
Scientific career
FieldsStructural biology
Cryo-electron microscopy
InstitutionsUniversity at Albany, Department of Biomedical Sciences
Columbia University College of Physicians and Surgeons, Department of Biochemistry and Molecular Biophysics
ThesisUntersuchungen von elektronenmikroskopischen Aufnahmen hoher Auflösung mit Bilddifferenz- und Rekonstruktionsverfahren (1970)
Doctoral advisorWalter Hoppe
Other academic advisorsRobert M. Glaeser, Robert Nathan


  1. Frank, Joachim (2017), Curriculum Vitae Archived 2017-10-09 at the Wayback Machine. Retrieved October 4, 2017.
  2. "The Nobel Prize in Chemistry 2017". The Nobel Foundation. October 4, 2017. Retrieved October 6, 2017.