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molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass

A macromolecule is a molecule with a large number of atoms. The word is usually used only when describing polymers, molecules which are made up of smaller molecules called monomers. All organic monomers are based on carbon, usually with hydrogen, oxygen and nitrogen. There are inorganic macromolecules based on other monomers.