After reaching around 597 kg (1,316 lb) and having been unable to leave his bed since 2001, Uribe lost about 181 kg (399 lb). It was one third of his body weight. He did this with the help of doctors and nutritionists. By the time of his death, Uribe was the world's third heaviest man. He was born in Monterrey, Nuevo León, Mexico.
Uribe died at the age of 48 from liver failure in Monterrey, Nuevo León, Mexico.
- "Half-ton Mexican man loses 200 pounds". chinadaily.com.cn. 2006-06-27.
- "Muere Manuel Uribe, quien fuera el hombre más obeso del mundo". Excélsior (in Spanish). 26 May 2014. Retrieved 26 May 2014.