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Serum is a clear, yellowish coloured fluid which is part of the blood. It does not contain white or red blood cells or a clotting factor. It is the blood plasma without the fibrinogens. Serum includes all proteins not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any extra substances (such as drugs and microorganisms).
Blood is centrifuged to remove cellular components. Anti-coagulated blood yields plasma containing fibrinogen and clotting factors. Coagulated blood (clotted blood) yields serum without fibrinogen, although some clotting factors remain.
- Martin, Elizabeth A., ed. (2007). Concise Medical Dictionary (7th ed.). Oxford: Oxford University Press. ISBN 0-19-280697-1. Retrieved 8 September 2009.
- Wang, Wendy; Srivastava, Sudhir (2002). "Serological Markers". In Breslow, Lester (ed.). Encyclopedia of Public Health. 4. New York, New York: Macmillan Reference USA. pp. 1088–1090.
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