User:Mr. Ibrahem/Abnormal uterine bleeding

Abnormal uterine bleeding
Other namesAtypical vaginal bleeding, dysfunctional uterine bleeding (DUB), abnormal vaginal bleeding
Medical specialtyGynecology
SymptomsIrregular, abnormally frequent, prolonged, or excessive amounts of uterine bleeding[1]
ComplicationsIron deficiency anemia[2]
CausesOvulation problems, fibroids, lining of the uterus growing into the uterine wall, uterine polyps, underlying bleeding problems, side effects from birth control, cancer[3]
Diagnostic methodBased on symptoms, blood work, medical imaging, hysteroscopy[2]
Differential diagnosisEctopic pregnancy
TreatmentHormonal birth control, GnRH agonists, tranexamic acid, NSAIDs, surgery[1][4]
FrequencyRelatively common[2]

Abnormal uterine bleeding (AUB), also known as atypical vaginal bleeding, is vaginal bleeding from the uterus that is abnormally frequent, lasts excessively long, is heavier than normal, or is irregular.[1][3] The term dysfunctional uterine bleeding was used when no underlying cause was present.[3] Vaginal bleeding after menopause is not normal.[5] Vaginal bleeding during pregnancy is excluded.[3] Iron deficiency anemia may occur and quality of life may be negatively affected.[6]

The underlying causes may include ovulation problems, fibroids, the lining of the uterus growing into the uterine wall, uterine polyps, underlying bleeding problems, side effects from birth control, or cancer.[3] More than one category of causes may apply in an individual case.[3] The first step in work-up is to rule out a tumor or pregnancy.[3][4] Medical imaging or hysteroscopy may help with the diagnosis.[2]

Treatment depends on the underlying cause.[2][3] Options may include hormonal birth control, gonadotropin-releasing hormone (GnRH) agonists, tranexamic acid, NSAIDs, and surgery such as endometrial ablation or hysterectomy.[1][4] AUB affects about 20% of reproductive aged women.[2]

References

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  1. 1.0 1.1 1.2 1.3 "Abnormal Uterine Bleeding". ACOG. March 2017. Archived from the original on 11 September 2018. Retrieved 11 September 2018.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Whitaker L, Critchley HO (July 2016). "Abnormal uterine bleeding". Best Pract Res Clin Obstet Gynaecol. 34: 54–65. doi:10.1016/j.bpobgyn.2015.11.012. PMC 4970656. PMID 26803558.
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Bacon, JL (June 2017). "Abnormal Uterine Bleeding: Current Classification and Clinical Management". Obstetrics and Gynecology Clinics of North America. 44 (2): 179–193. doi:10.1016/j.ogc.2017.02.012. PMID 28499529.
  4. 4.0 4.1 4.2 Cheong, Y; Cameron, IT; Critchley, HOD (1 September 2017). "Abnormal uterine bleeding". British Medical Bulletin. 123 (1): 103–114. doi:10.1093/bmb/ldx027. PMID 28910998.
  5. Sung, Sharon; Abramovitz, Aaron (2023). "Postmenopausal Bleeding". StatPearls. StatPearls Publishing. PMID 32965859. Archived from the original on 2023-03-24. Retrieved 2023-10-30.
  6. Kovalenko, Mariya; Velji, Zain Azim; Cheema, Jaspreet; Datta, Shreelata (1 November 2021). "Intermenstrual and postcoital bleeding". Obstetrics, Gynaecology & Reproductive Medicine. 31 (11): 310–316. doi:10.1016/j.ogrm.2021.09.003. ISSN 1751-7214.