User:Mr. Ibrahem/Hypertriglyceridemia
Hypertriglyceridemia | |
---|---|
Triglyceride, which cause hypertriglyceridemia at high level | |
Medical specialty | Endocrinology |
Symptoms | Usually none[1] |
Complications | Cardiovascular disease, pancreatitis[2] |
Risk factors | Obesity, diabetes, genetics, metabolic syndrome, alcohol[2] |
Diagnostic method | Triglycerides > 150 mg/dL (1.7 mmol/L)[2] |
Treatment | Not drinking alcohol, weight loss, avoiding simple carbohydrates, controlling blood sugar[2] |
Medication | Fibrates, omega-3 fatty acids, insulin[2][3] |
Frequency | ~30% (USA)[4] |
Hypertriglyceridemia is high (hyper-) blood levels (-emia) of triglycerides.[1] High triglycerides itself is usually symptomless, although high levels may be associated with skin lesions known as xanthomas.[1] Complications may include cardiovascular disease and pancreatitis.[2] Generally only severe disease results in pancreatitis.[2] High triglycerides may occur alone or with other lipid disorders.
Most cases result from a combination of factors.[4] Common risk factors include obesity, diabetes, genetics, and metabolic syndrome.[2] Other risks include alcohol, hypothyroidism, kidney problems, lupus, and certain medications such as protease inhibitors and birth control pills.[2][4] Diagnosis is based on fasting triglycerides of greater than than 150 mg/dL (1.7 mmol/L).[2] Moderate disease is 150 to 1,000 mg/dL (1.7 to 11.4 mmol/L) while severe disease is greater than 1,000 mg/dL (>11.4 mmol/L).[2]
Treatment includes not drinking alcohol, weight loss, avoiding simple carbohydrates, and controlling blood sugar.[2] Medications are generally not required, though fibrates and omega-3 fatty acids may help.[2] In those with pancreatitis due to high triglycerides treatment is with intravenous fluids, insulin, and potentially plasmapheresis.[2][3] High blood triglycerides affects about 30% of people in the United States and is more common in males and older people.[4] Very high levels affect about 2% of people.[4]
References
change- ↑ 1.0 1.1 1.2 "High Blood Triglycerides | NHLBI, NIH". www.nhlbi.nih.gov. Archived from the original on 9 October 2020. Retrieved 5 October 2020.
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 Parhofer, KG; Laufs, U (6 December 2019). "The Diagnosis and Treatment of Hypertriglyceridemia". Deutsches Arzteblatt international. 116 (49): 825–832. doi:10.3238/arztebl.2019.0825. PMID 31888796.
- ↑ 3.0 3.1 Rawla, P; Sunkara, T; Thandra, KC; Gaduputi, V (December 2018). "Hypertriglyceridemia-induced pancreatitis: updated review of current treatment and preventive strategies". Clinical journal of gastroenterology. 11 (6): 441–448. doi:10.1007/s12328-018-0881-1. PMID 29923163.
- ↑ 4.0 4.1 4.2 4.3 4.4 Karanchi, H; Muppidi, V; Wyne, K (January 2020). "Hypertriglyceridemia". PMID 29083756.
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