Thiamine

chemical compound
(Redirected from Vitamin B1)

Thiamine (or thiamin) is vitamin B1. It is a water-soluble vitamin of the B complex. Its phosphate derivatives take part in many cellular processes. Thiamine pyrophosphate (TPP) is a coenzyme in the catabolism of sugars and amino acids.

Thiamine
Thiamin.svg
Thiamine cation 3D ball.png
Skeletal formula and ball-and-stick model of the cation in thiamine
Clinical data
Pronunciation/ˈθ.əmɪn/ THY-ə-min
SynonymsVitamin B1, aneurine, thiamin
AHFS/Drugs.comMonograph
License data
Routes of
administration
by mouth, IV, IM[1]
Drug classvitamin
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability3.7% to 5.3% Template:Medical citation needed
Elimination half-life1.8d[2][better source needed]
Identifiers
  • 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
CAS Number
PubChem CID
PubChem SID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC12H17N4OS+
Molar mass265.36 g·mol−1
3D model (JSmol)
  • cation: Cc2ncc(C[n+]1csc(CCO)c1C)c(N)n2
  • cation: InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1 checkY
  • Key:JZRWCGZRTZMZEH-UHFFFAOYSA-N

also it can be found in Food and Manufactured Dietary supplements also in Medications[1][3] Foods that provide Thiamine include whole grains, Legume[1]

Lack of thiamine causes beriberi.

ReferencesEdit

  1. 1.0 1.1 1.2 "Thiamin Fact Sheets for Health Professionals". Office of Dietary Supplements. 11 February 2016. Archived from the original on 30 December 2016. Retrieved 30 December 2016.
  2. Royer-Morrot MJ, Zhiri A, Paille F, Royer RJ (1992). "Plasma thiamine concentrations after intramuscular and oral multiple dosage regimens in healthy men". European Journal of Clinical Pharmacology. 42 (2): 219–22. doi:10.1007/BF00278489. PMID 1618256. S2CID 19924442.
  3. "Thiamine: MedlinePlus Drug Information". medlineplus.gov. Retrieved 30 April 2018.