immune responses of an organism against its own healthy cells and tissues due to failure of an organism in recognizing its own constituent parts as self

Autoimunity is immune reaction against self components, which are recognized as antigens. This reaction can produce severe inflammation or can be innocuous, as when directed to intracellular autoantigens, which are not expressed to circulating antibodies or to the lymphocytes.[1]

Autoimunity can develop spontaneously or can be induced experimentally by immunization with autoantigens or antigensd croos-reactive with autoantigens. Autoimunity reactions cause numerous autoimmune diseases and disorders.[2]

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  1. Lawrence E., Ed., ed. (1999). Henderson's Dictionary of Biological Terms. London: Longman. ISBN 0-582-22708-9.
  2. Hadžiselimović R., Pojskić N. (2005). Uvod u humanu imunogenetiku / Introduction to Human Immunogenetics. Sarajevo: INGEB. ISBN 9958-9344-3-4.

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