Multiple organ dysfunction syndrome

altered organ function in an acutely ill patient requiring medical intervention to achieve homeostasis.
(Redirected from Multiple organ failure)

Multiple organ dysfunction syndrome (MODS), previously known as multiple organ failure (MOF), Total organ failure(TOF) or multisystem organ failure (MSOF), is when the organ function is acutely ill and the patient is required medical intervention to achieve homeostasis. It usually involves two or more organ systems.[1]

The use of "multiple organ failure" or "multisystem organ failure" should be avoided since that phrase was based upon physiological parameters to determine whether or not a particular organ was failing.[1]

Cause Edit

The condition usually results from infection, injury (accident, surgery), hypoperfusion and hypermetabolism. The primary cause triggers an uncontrolled inflammatory response. Sepsis is the most common cause in operative and non-operative patients. Sepsis may result in septic shock.

Stages Edit

Four clinical phases have been suggested:

References Edit

  1. 1.0 1.1 Intensive Care Medicine Archived 2006-04-22 at the Wayback Machine by Irwin and Rippe

Other websites Edit