Fry was born in Hampstead, London and grew up in Norfolk. His maternal grandparents were Hungarian Jews. He is a Jewish atheist and is openly gay. He has been diagnosed with cyclothymia, a mild form of bipolar disorder. From 1995-2010, Fry had a relationship with Daniel Cohen. In January 2015, Fry married his partner, Elliot Spencer.
In February 2018, Fry announced via a video that he had an operation to treat prostate cancer and have 11 lymph nodes removed and was recovering from the surgery. He described the cancer as aggressive and said that early intervention had saved his life.
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- Khomani, Nadia (23 February 2018). "Stephen Fry has prostate cancer". The Guardian. Retrieved 23 February 2018. CS1 maint: discouraged parameter (link)
- "Stephen Fry recovering from prostate cancer surgery". 23 February 2018.