U.S. Route 425

U.S. Route 425 (US 425) is a north–south United States highway in the U.S. states of Mississippi, Louisiana, and Arkansas. Its north end is Pine Bluff, Arkansas, and its south end is Natchez, Mississippi.

U.S. Route 425
Major junctions
From	US 61 / US 84 at Natchez, MS
Major intersections	I-20 at Rayville, LA
To	I-530 / US 63 / US 65 / US 79 at Pine Bluff, AR
Location
Country	United States
Highway system
United States Numbered Highway System List Special Divided